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EGLUMETAD
SynDRA canonical compound SYN0000301 — structure-anchored drug synonym record
| Clinical phase | Phase 2 |
|---|
| Primary target(s) | GRM3 |
|---|
| Mechanism of action | Glutamate receptor agonist |
|---|
All known targets
Mechanisms of action (all sources)
- Glutamate receptor agonist
- GRM2 FULL AGONIST
- GRM3 FULL AGONIST
- GRM6 FULL AGONIST
- GRM8 FULL AGONIST
- GRM3 AGONIST
- GRM2 AGONIST
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ADGRF1
- GRM5
- TDG
- SMUG1
- S1PR1
- NTHL1
- NEIL2
- NEIL1
- MUTYH
- MPG
- MBD4
- HDAC6
- GRM7
- GRM4
- ADRA2A
- GRM1
- GPR35
- GPR119
- GLP1R
- FPR2
- FFAR4
- CX3CR1
- C5AR1
- APLNR
- AGTR1
- ADRB2
- UNG
Cross-references
Synonyms
- Eglumetad anhydrous
- LY-354740
- LY354740
- Eglumegad
- (1S,2S,5R,6S)-2-aminobicyclo[310]hexane-2,6-dicarboxylic acid
- Eglumegad [INN]
- UNII-ONU5A67T2S
- LY 354740
- ONU5A67T2S
- CHEMBL8759
- Eglumegad (INN)
- (1S,2S,5R,6S)-2-Aminobicyclo(310)hexane-2,6-dicarboxylic acid
- (1R,4S,5S,6S)-4-aminobicyclo[310]hexane-4,6-dicarboxylic acid
- (1S,2S,5R,6S)-2-Amino-bicyclo[310]hexane-2,6-dicarboxylic acid
- [3H]Eglumegad
- LY366563
- Eglumetad [USAN:INN]
- (+)-2-Aminobicyclo(310)hexane-2,6-dicarboxylic acid
- 40F
- PubChem18158
- Eglumegad [USAN]
- Eglumegad hydrate
- Eglumetad hydrate
- LY-314582
- LY-366563
- LY314582
- Eglumegad (USAN)
- LY-354740 monohydrate
- Eglumetad (INN/USAN)
- (1R,4S,5S,6S)-4-aminobicyclo[310]hexane-4,6-dicarboxylic acid hydrate
- (1S,2S,5R,6S)-2-Aminobicyclo(310)hexane-2,6-dicarboxylic acid monohydrate
- 2-Aminobicyclo(310)hexane-2,6-dicarboxylic acid
- 4-aminobicyclo[310]hexane-4,6-dicarboxylic acid
- (+)-2-Aminobicyclo(3.1.0)hexane-2,6-dicarboxylic acid
- RefChem:1048900
- DTXCID5092585
- (rel)-Eglumegad
- LY 354740 Hydrate
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