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LINOLEIC ACID
SynDRA canonical compound SYN0000298 — structure-anchored drug synonym record
| Clinical phase | Phase 3 |
|---|
| Primary target(s) | FABP4 | FFAR1 | FFAR4 | HNF4A | KCNB1 | PPARG | TRPM8 |
|---|
| Mechanism of action | oxidative stress inducer |
|---|
All known targets
- FABP4
- KCNB1
- PPARG
- FFAR1
- FFAR4
- NR4A2
- PTGS2
- PTGS1
- PPARD
- PPARA
- AKR1C3
- LOX1.1
Mechanisms of action (all sources)
- oxidative stress inducer
- FABP4 INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ALDH1A1
- ALOX15
- TSHR
- TERT
- TDP1
- SIRT6
- RXRA
- RBP4
- PTPN7
- POLL
- POLK
- NR1H4
- LMNA
- KAT2A
- HSD17B10
- HPGD
- GMNN
- ESR1
- DUSP3
- CYP3A4
- AR
- USP1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- CP2C9
- CP2CJ
- CP2D6
- CP3A4
- FABP5
- GCR
- GLI3
- HSPB1
- KCNKA
- LOX15
- NF2L2
- NR1I2
- PHGDH
- RARA
- TP53
Cross-references
Synonyms
- alpha-Linoleic acid
- linolic acid
- 9,12-linoleic acid
- C18:2 (n-6)
- Emersol 315
- Linoleate
- Linolic acid
- Polylin 515
- Ronacare asc 3
- Unifac 6550
- FEMA NO. 3380, LINOLEIC ACID-
- NSC-281243
- Linoleic acid component of vitamin f
- Telfairic acid
- (9Z,12Z)-octadeca-9,12-dienoic acid
- cis,cis-Linoleic acid
- Grape seed oil
- cis,cis-9,12-Octadecadienoic acid
- cis-9,cis-12-Octadecadienoic acid
- 9,12-Linoleic acid
- 9Z,12Z-Linoleic acid
- Extra Linoleic 90
- 9-cis,12-cis-Linoleic acid
- Emersol 310
- Polylin No. 515
- Oils, grape
- 9Z,12Z-octadecadienoic acid
- all-cis-9,12-Octadecadienoic acid
- Linoleic
- acide linoleique
- (Z,Z)-9,12-Octadecadienoic acid
- acido lino
- (z,z) 9,12-octadecadienoic acid
- Leinoleic acid
- 9,12-Octadecadienoic acid (9Z,12Z)-
- 9,12-Octadecadienoic acid (Z,Z)-
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