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CLORGILINE
SynDRA canonical compound SYN0000297 — structure-anchored drug synonym record
| Clinical phase | Phase 2 |
|---|
| Primary target(s) | MAOA |
|---|
| Mechanism of action | Monoamine oxidase inhibitor |
|---|
All known targets
Mechanisms of action (all sources)
- Monoamine oxidase inhibitor
- MAOA INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- MAOB
- ACHE
- HDAC8
- HIF1A
- HPGD
- HRH3
- HSD17B10
- KCNH2
- KDM1A
- KDM4E
- KMT2A
- KMT5A
- MAPK1
- HDAC5
- MAPT
- NPC1
- PIN1
- PRMT1
- RAB9A
- RGS4
- SAMHD1
- TDP1
- THPO
- TSHR
- HDAC6
- HDAC3
- ALDH1A1
- CA7
- APP
- ARSA
- ATAD5
- BCHE
- CA1
- CA12
- CA2
- CA4
- CA5A
- CA5B
- CASP3
- HDAC2
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- 5HT2A
- AHR
- CASP1
- CFTR
- CP1A2
- CP2C9
- CP2CJ
- CP2D6
- DRD2
- ESR1
- NF2L2
- NLRP1
- NR1I2
- PHGDH
- PRGR
Drug classes
- Antidepressive Agents
- Monoamine Oxidase Inhibitors
Cross-references
Synonyms
- Clorgilina
- M&B-9302
- Clorgyline
- Chlorgyline
- Clorgilin
- Clorgilinum
- Clorgiline [INN]
- M and B 9302
- Clorgilina [INN-Spanish]
- Clorgiline (INN)
- Clorgilinum [INN-Latin]
- M & B 9302
- N-methyl-n-propargyl-3-(2,4-dichlorophenoxy)propylamine
- N-(3-(2,4-Dichlorophenoxy)propyl)-N-methyl-2-propynylamine
- N-[3-(2,4-DICHLOROPHENOXY)PROPYL]-N-METHYL-N-PROP-2-YNYLAMINE
- 2-Propyn-1-amine, N-(3-(2,4-dichlorophenoxy)propyl)-N-methyl-(9CI)
- 3-(2,4-dichlorophenoxy)-N-methyl-N-prop-2-ynylpropan-1-amine
- LYJ16FZU9Q
- N-(3-(2,4-dichlorophenoxy)propyl)-N-methylprop-2-yn-1-amine
- N-[3-(2,4-dichlorophenoxy)propyl]-N-methylprop-2-yn-1-amine
- CHEBI:3763
- RefChem:127097
- DTXCID9028419
- n-methyl-n-propargyl-3-(2,4-dichlorophenoxy)propylamine
- 2-Propynylamine, N-(3-(2,4-dichlorophenoxy)propyl)-N-methyl-
- UNII-LYJ16FZU9Q
- CAS-17780-75-5
- BRN 1976758
- BTFHLQRNAMSNLC-UHFFFAOYSA-N
- Clorgiline [INN:BAN]
- Prestwick0_000344
- Prestwick1_000344
- Prestwick2_000344
- Prestwick3_000344
- Lopac-M-3778
- Lopac0_000746
- SCHEMBL61914
- BSPBio_000407
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