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MOLINDONE
SynDRA canonical compound SYN0000264 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | HTR2A |
|---|
| Mechanism of action | Dopamine receptor antagonist |
|---|
| Indication | schizophrenia |
|---|
| Disease area | neurology/psychiatry |
|---|
All known targets
- DRD2
- HTR2A
- HRH1
- ADRA1A
- Drd2
- Htr2a
- HTR7
- HTR6
- HTR2C
- HTR1A
- Drd1
- ADRA2A
Mechanisms of action (all sources)
- Dopamine receptor antagonist
- DRD2 ANTAGONIST
- Dopamine D2 receptor antagonist
- HTR2A ANTAGONIST
- Serotonin 2a (5-HT2a) receptor antagonist
- HRH1 ANTAGONIST
- DRD2 BINDER
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ADRB2
- HTR2B
- ADORA1
- OPRK1
- KCNH2
- LMNA
- MAOA
- MC3R
- MC4R
- MLNR
- MPHOSPH8
- NPY1R
- NR1I2
- NR3C1
- OPRD1
- PDE3A
- OPRM1
- PDE4D
- PGR
- PLAUR
- PTGS2
- RGS4
- SAMHD1
- SLC29A1
- SLC6A2
- SLC6A3
- SLC6A4
- TBXA2R
- HTR3A
- HRH3
- ADORA2A
- CHRM1
- ADORA3
- ADRB1
- AGTR1
- ARSA
- AVPR1A
- AVPR2
- BDKRB2
- BLM
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- COMT
- CP2D6
- CP3A7
- GAMT
- GNMT
- HNMT
- NNMT
- PNMT
Drug classes
- Antipsychotic Agents
- Central Nervous System Agents
- Central Nervous System Depressants
- Psychotropic Drugs
- Tranquilizing Agents
- Typical Antipsychotic
ATC classes
Cross-references
Synonyms
- MOBAN
- MOLINDONE HYDROCHLORIDE
- (+/-)-Molindone
- molindone hydrochloride
- moban
- molindone HCl
- molindone monohydrochloride
- Molindona
- Spn-810
- SPN-810
- Molindone hydrochloride
- Molindone HCl
- Lidone
- Molindone (hydrochloride)
- EN-1733A
- EN 1733 A
- EN300-51039
- DSSTox_RID_80866
- DSSTox_CID_25417
- DSSTox_GSID_45417
- SMR000499578
- Molindonum
- Molindone Monohydrochloride
- Molindona [INN-Spanish]
- Molindone (INN)
- Molindone (MOL)
- Molindone [INN:BAN]
- Molindonum [INN-Latin]
- (+-)-Molindone
- RT3Y3QMF8N
- RefChem:56582
- DTXCID603332
- N05AE02
- MOLINDONE [INN]
- HSDB 3131
- UNII-RT3Y3QMF8N
- Molindon
- MOLINDONE [MI]
Reported adverse events
- Akathisia
- Akinesia
- Dyskinesia
- Dystonia
- Tardive dyskinesia
- Urinary retention
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