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KETANSERIN
SynDRA canonical compound SYN0000258 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Primary target(s) | HTR2C |
|---|
| Mechanism of action | Serotonin receptor antagonist |
|---|
| Indication | hypertension |
|---|
| Disease area | cardiology |
|---|
All known targets
- HTR2C
- HTR2A
- DRD5
- HTR1A
- ADRA1B
- ADRA1D
- SLC18A2
- SLC18A1
- HTR5A
- HTR2B
- DRD1
- ADRA1A
Mechanisms of action (all sources)
- Serotonin receptor antagonist
- HTR1A ANTAGONIST
- HTR1B ANTAGONIST
- HTR1D ANTAGONIST
- HTR2A ANTAGONIST
- HTR2B ANTAGONIST
- HTR2C ANTAGONIST
- HTR5A ANTAGONIST
- HTR7 ANTAGONIST
- ADRA1A ANTAGONIST
- ADRA1B ANTAGONIST
- ADRA1D ANTAGONIST
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- DRD3
- ADRA2C
- ACHE
- PDE3A
- OPRM1
- OPRK1
- OPRD1
- NR3C1
- NPY1R
- NPSR1
- MLNR
- MC4R
- PDE4D
- MC3R
- MAPT
- MAPK1
- MAOA
- LMNA
- KDR
- KDM4E
- IDH1
- PDE4A
- PGR
- HSD17B10
- SLC6A2
- TSHR
- TP53
- TDP1
- TBXA2R
- SLCO1B3
- SLCO1B1
- SLC6A4
- SLC6A3
- SLC29A1
- PIN1
- SETD7
- SAMHD1
- RAPGEF4
- PTH1R
- PTGS2
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- 5HT1A
- CP2C9
- PHGDH
- KSYK
- ID4
- GPR32
- ESRRA
- CP3A7
- CP2D6
- CP2CJ
- ADA1D
- 5HT1B
- ADA1B
- ADA1A
- 5HT7R
- 5HT5A
- 5HT2C
- 5HT2B
- 5HT2A
- 5HT1D
- SYK
Drug classes
- Antihypertensive Agents
- Cardiovascular Agents
- Hematologic Agents
- Neurotransmitter Agents
- Platelet Aggregation Inhibitors
- Serotonin Agents
- Serotonin Antagonists
ATC classes
- C02K · OTHER ANTIHYPERTENSIVES
Cross-references
Synonyms
- R 41 468
- ketensin
- suffrexal
- ketanserin tartrate hydrate
- ketanserin tartrate
- R 41468
- Ketanserine
- Ketanserina
- KETANSERIN TARTRATE
- Perketan
- Serepress
- KJK 945
- NSC-758959
- R-49945
- R-41,468
- R-41468
- Sufrexal
- Ketanserinum
- Ketaserin
- Perketal
- Serefrex
- Taseron
- Ketanserina [INN-Spanish]
- Ketanserine [INN-French]
- Ketanserinum [INN-Latin]
- [3H]-Ketanserin
- Ketanserin (USAN/INN)
- Ketanserin [USAN:BAN:INN]
- (+)-3-[2-[4-(4-Fluorobenzoyl)-1-piperidinyl]ethyl]-2,4(1H,3H)-quinazolinedione
- 3-(2-(4-(4-Fluorobenzoyl)piperidinol)ethyl)-2,4(1H,3H)-quinazolinedione
- 3-(2-(4-(p-Fluorobenzoyl)piperidino)ethyl)-2,4-(1H,3H)-quinazolinedione
- 3-(2-{4-[(4-fluorophenyl)carbonyl]piperidin-1-yl}ethyl)quinazoline-2,4(1H,3H)-dione
- 3-[2-[4-(4-fluorobenzoyl)-1-piperidyl]ethyl]-1H-quinazoline-2,4-dione
- 3-[2-[4-(4-fluorobenzoyl)piperidin-1-yl]ethyl]-1H-quinazoline-2,4-dione
- 3-{2-[4-(4-fluorobenzoyl)piperidin-1-yl]ethyl}quinazoline-2,4(1H,3H)-dione
- R 41,468
- NSC 758959
- CHEBI:6123
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