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BAICALEIN
SynDRA canonical compound SYN0000255 — structure-anchored drug synonym record
| Clinical phase | Preclinical |
|---|
| Primary target(s) | ALOX12 | ALOX5 | GLO1 | PREP | SELL | SELP | TNF | XDH |
|---|
| Mechanism of action | lipoxygenase inhibitor |
|---|
All known targets
- ALOX5
- GLO1
- PREP
- SELL
- SELP
- TNF
- XDH
- ALOX12
Mechanisms of action (all sources)
- lipoxygenase inhibitor
- GLO1 INHIBITOR
- TNF INHIBITOR
- XDH INHIBITOR
- SELL INHIBITOR
- PREP INHIBITOR
- SELP INHIBITOR
- ALOX5 INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- HSD17B3
- CYP1A1
- UGT1A1
- SNCA
- POLH
- PLK1
- KDM4E
- HDAC8
- HDAC6
- GRK6
- CYP3A4
- CYP1B1
- YES1
- ALOX15
- CYP1A2
- RECQL
- MGAM
- MUC1
- NR3C1
- PGR
- PIM1
- PIN1
- APEX1
- PLK3
- ALOX15B
- POLI
- POLK
- PTPRS
- RAPGEF3
- SAMHD1
- CYCS
- SELE
- SI
- SLCO1B1
- SLCO1B3
- SMN1
- TDP1
- THRB
- TP53
- ALDH1A1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ABL1
- NTM1A
- GABRG1
- GABRG2
- GABRG3
- GABRP
- GABRQ
- IFNG
- KSYK
- LMBL1
- LOX15
- NR0B1
- NSD2
- NTMT1
- GABRD
- NUDT15
- PAFA
- PHGDH
- PIP4K2A
- PRSS1
- PRSS2
- PRSS3
- PSIP1
- RIN1
- SMCA2
- SYK
- GABRE
- GABRB3
- AK1C4
- CSNK2A1
- AURKB
- CASP6
- CCNB1
- CDK1
- CIB1
- CLK1
- CP1A2
- CP2C9
- CP2CJ
- CP2D6
Drug classes
- Antioxidants
- Enzyme Inhibitors
- Prostaglandin Antagonists
Cross-references
Synonyms
- Noroxylin
- NSC-661431
- 5,6,7-Trihydroxyflavone
- 5,6,7-trihydroxy-2-phenyl-4H-chromen-4-one
- Biacalein
- BaiKalein
- Baicelein
- UNII-49QAH60606
- NSC661431
- NSC 661431
- CHEMBL8260
- 5,6,7-trihydroxy-2-phenylchromen-4-one
- CHEBI:2979
- FXNFHKRTJBSTCS-UHFFFAOYSA-N
- MFCD00017459
- 4H-1-Benzopyran-4-one, 5,6,7-trihydroxy-2-phenyl-
- 49QAH60606
- 5,7-Trihydroxyflavone
- 5,6,7-trihydroxy-2-phenyl-chromen-4-one
- Sho-saiko-to
- SMR000112462
- SR-01000597499
- Baicalein, 8
- Baicalein,(S)
- 3WL
- Baicalein, 14
- Baicalein, 98%
- AC1NQYPP
- Tocris-1761
- 5,6,7-Trihydroxy-2-phenyl-4H-1-benzopyran-4-one
- Spectrum_000427
- SpecPlus_000758
- BAICALEIN [MI]
- BAICALEIN [INCI]
- Spectrum2_000466
- Spectrum3_001608
- Spectrum4_000537
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