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DAIDZEIN
SynDRA canonical compound SYN0000243 — structure-anchored drug synonym record
| Clinical phase | Phase 2 |
|---|
| Primary target(s) | ESRRA | ESRRB | ESRRG | TRPC5 |
|---|
| Mechanism of action | estrogen receptor agonist |
|---|
All known targets
- ESRRA
- ESRRB
- ESRRG
- TRPC5
- AKR1B1
- ESR1
- ESR2
Mechanisms of action (all sources)
- ESRRA AGONIST
- ESRRB AGONIST
- ESRRG AGONIST
- TRPC5 MODULATOR
- ESR1 AGONIST
- TRPC5 ACTIVATOR
- ESR1 INHIBITOR
- ESR2 INHIBITOR
- AKR1B1 INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- UGT1A1
- ALDH2
- CA7
- CA4
- CA12
- HDAC6
- ABCC1
- PSMB5
- RACGAP1
- RAB9A
- PTPN1
- PTH1R
- PPARG
- RORC
- PPARD
- PPARA
- PON1
- PMP22
- PKM
- NR3C1
- RGS4
- SLCO1B3
- SETD7
- SLCO1B1
- NFKB1
- SLCO2B1
- SMN1
- TDP1
- THPO
- THRB
- TOP1
- TOP2A
- TP53
- TTR
- UGT1A10
- UGT1A4
- NPC1
- LMNA
- NFE2L2
- MAPT
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- 5HT2A
- BAP1
- SMN
- RGAP1
- RARA
- PIM2
- NTM1A
- NR1I2
- NF2L2
- MRGPRX1
- HTT
- HDAC9
- GLI3
- GCR
- ERR3
- CP3A7
- CP3A4
- CP2D6
- CP2CJ
- CP2C9
- CP1A2
- YAP1
Drug classes
Cross-references
Synonyms
- 4',7-dihydroxyisoflavone
- 4',7-Dihydroxyisoflavone
- Daidzeol
- 7,4'-Dihydroxyisoflavone
- 7-hydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one
- 4H-1-Benzopyran-4-one, 7-hydroxy-3-(4-hydroxyphenyl)-
- 7-Hydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
- 7-hydroxy-3-(4-hydroxyphenyl)chromen-4-one
- 7-Hydroxy-3-(4-hydroxyphenyl)-4-benzopyrone
- UNII-6287WC5J2L
- CCRIS 7600
- K 251b
- 4,7-Dihydroxyisoflavone
- EINECS 207-635-4
- BRN 0231523
- CHEMBL8145
- 4',7-Dihydroxy-iso-flavone
- d-(+)-alpha-methylbenzylamine
- ,7-Dihydroxyisoflavone
- DIADZEIN
- DTXCID102310
- CHEBI:28197
- Diadzein
- RefChem:5729
- MFCD00016954
- Daidzein (Standard)
- 7-Hydroxy-3-(4-hydroxy-phenyl)-chromen-4-one
- 4',7-dihydroxy-isoflavon
- CAS-486-66-8
- SMR000326832
- K-251b
- SR-01000075492
- formonometin
- Isoflavone, 4',7-dihydroxy-
- NPI-031E
- Daizeol;
- isoflavone aglycone
- Daidzein (DAI)
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