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MELATONIN
SynDRA canonical compound SYN0000231 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Primary target(s) | MTNR1B |
|---|
| Mechanism of action | Nitric oxide synthase inhibitor |
|---|
| Indication | sleep cycle support |
|---|
| Disease area | neurology/psychiatry |
|---|
All known targets
- MTNR1A
- MTNR1B
- HTR2B
- NQO2
- MPO
- ASMT
- CALM1
- CALR
- CYP1B1
- EPX
- ESR1
- HRH3
Mechanisms of action (all sources)
- Melatonin receptor agonist
- Nitric oxide synthase inhibitor
- MTNR1A AGONIST
- MTNR1B AGONIST
- HTR2B ANTAGONIST
- MTNR1A FULL AGONIST
- MTNR1B FULL AGONIST
- MTNR1A BINDER
- NQO2 INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- NR1I2
- HTR1A
- MMP9
- MAPK14
- MAPK3
- MBD4
- MC3R
- MC4R
- MC5R
- MLNR
- MMP1
- MPG
- MAOB
- MPHOSPH8
- MUTYH
- NEIL1
- NEIL2
- NFE2L2
- NOS1
- NOTUM
- MAPK1
- ACHE
- NPY1R
- LCK
- HDAC6
- HMGCR
- HPGD
- HRH1
- HRH2
- HRH4
- HSD17B10
- HTR1B
- HTR1D
- HTR2A
- HTR2C
- HTR3A
- HTR6
- HTR7
- KCNH2
- KDM4E
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- 5HT2A
- 5HT2B
- AHR
- CP1A2
- CP2C9
- CP2CJ
- CP2D6
- CP3A4
- M4K2
Drug classes
- Antioxidants
- Central Nervous System Agents
- Central Nervous System Depressants
- Protective Agents
ATC classes
- N05C · HYPNOTICS AND SEDATIVES
Cross-references
Synonyms
- Melatonex
- melatol
- melatonine
- circadin
- 5-methoxy n-acetyl-tryptamine
- Melatol
- Melatonine
- Melovine
- Regulin
- Tartrol
- BCI-049
- J5.258B
- NSC-113928
- NSC-302012
- NSC-56423
- Circadin
- General nutrit
- Health aid
- Heidadouppi
- Icenia
- Life ext
- Melapure
- Melatonin neurim
- Natrol
- Nature's blend
- Natures bounty
- Quality health
- S.gard
- Slenyto
- Travelag
- Vespro
- Vytalonin
- N-Acetyl-5-methoxytryptamine
- 5-Methoxy-N-acetyltryptamine
- N-[2-(5-methoxyindol-3-yl)ethyl]acetamide
- UNII-JL5DK93RCL
- N-(2-(5-Methoxyindol-3-yl)ethyl)acetamide
- N-acetyl-5-methoxy-tryptamine
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