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TYRPHOSTIN AG-1478
SynDRA canonical compound SYN0000222 — structure-anchored drug synonym record
| Clinical phase | Preclinical |
|---|
| Primary target(s) | EGFR | MAPK14 |
|---|
| Mechanism of action | EGFR inhibitor |
|---|
All known targets
Mechanisms of action (all sources)
- EGFR INHIBITOR
- MAPK14 INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- NOD1
- LCK
- PIM2
- NTRK2
- NUAK1
- PAK2
- PAK3
- PAK4
- PAK5
- PAK6
- PASK
- PDGFRA
- PDGFRB
- PDPK1
- PHKG2
- PIM1
- PIM3
- NOD2
- PKMYT1
- PKN2
- PLK1
- PLK2
- PLK3
- PMP22
- PRKACA
- PRKCA
- PRKCB
- PRKCD
- PRKCE
- PRKCG
- NTRK1
- ABL1
- PRKCI
- NLK
- MAPK3
- MAPK8
- MAPK9
- MAPKAPK2
- MAPKAPK3
- MAPKAPK5
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Cross-references
Synonyms
- Tyrphostin AG 1478
- AG 1478
- N-(3-chlorophenyl)-6,7-dimethoxyquinazolin-4-amine
- 4-(3-Chloroanilino)-6,7-dimethoxyquinazoline
- AG1478
- TYRPHOSTIN
- 4-Quinazolinamine, N-(3-chlorophenyl)-6,7-dimethoxy-
- UNII-SUH0SEZ9HY
- SUH0SEZ9HY
- AG-1478 hydrochloride
- AG-1478 (Tyrphostin AG-1478)
- CHEMBL7917
- CHEBI:75404
- N-(3-Chlorophenyl)-6,7-dimethoxy-4-quinazolinamine
- NSC-693255
- AK-63142
- N-(3-chlorophenyl)-6,7-dimethoxy-quinazolin-4-amine
- BRD6408
- BRD-6408
- SR-01000076156
- NSC693255
- BRD-K68336408
- tyrphostin-AG-1478
- AG-1478 free base
- (3-Chlorophenyl)(6,7-dimethoxyquinazolin-4-yl)amine
- RefChem:389357
- tyrphostin AG1478
- MFCD00270914
- Tyrphostin AG-1478;NSC 693255
- Tocris-1276
- InSolution AG 1478
- BiomolKI_000018
- Maybridge1_004001
- Lopac-T-4182
- BiomolKI2_000028
- CBiol_002058
- Lopac0_001127
- Oprea1_653581
- SCHEMBL93838
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