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ROTENONE
SynDRA canonical compound SYN0000218 — structure-anchored drug synonym record
| Primary target(s) | ND1 |
|---|
| Mechanism of action | Mitochondrial complex I inhibitor |
|---|
All known targets
Mechanisms of action (all sources)
- Mitochondrial complex I inhibitor
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ABCB11
- CYP19A1
- MT-ND4
- MTOR
- CYP2C19
- ESR1
- ESR2
- TP53
- HTR6
- NPY1R
- NPY2R
- MMP1
- NR3C1
- NPSR1
- NPC1
- NFE2L2
- OPRD1
- MPHOSPH8
- MMP9
- MC4R
- MC5R
- OPRM1
- MC3R
- MAPT
- MAPK3
- MAPK14
- MAPK1
- MAOA
- LMNA
- LCK
- KDM4E
- KCNH2
- JUN
- OPRK1
- PDE5A
- HTR2B
- PMP22
- USP1
- TSHR
- THRB
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- 5HT2A
- MDR1
- SYK
- SMAD3
- SMAD2
- RARA
- PRGR
- NSD2
- NR1H4
- NPR2
- NPR1
- NF2L2
- KSYK
- ANDR
- GLSK
- GLI3
- GEMI
- ESRRA
- CP3A4
- CP2D6
- CP2CJ
- CP2C9
- CP1A2
- CP19A
- YAP1
Drug classes
- Insecticides
- Uncoupling Agents
Cross-references
Synonyms
- Paraderil
- Dactinol
- Tubatoxin
- (-)-Rotenone
- Barbasco
- (-)-cis-Rotenone
- Derris
- Derrin
- Cube root
- Rotocide
- Nicouline
- Rotenon
- Noxfish
- Ronone
- Deril
- Canex
- Liquid Derris
- Cube-Pulver
- Dri-Kil
- Rotessenol
- Rotenox
- Rotefive
- Noxfire
- Rotefour
- Mexide
- Haiari
- Cubor
- Derris root
- Powder and root
- Pro-nox fish
- Chem-Mite
- Cenol garden dust
- Curex flea duster
- Prenfish
- Prentox
- Gerane
- Synpren
- Ro-Ko
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