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GENISTEIN
SynDRA canonical compound SYN0000206 — structure-anchored drug synonym record
| Clinical phase | Phase 2/Phase 3 |
|---|
| Primary target(s) | ESR2 |
|---|
| Mechanism of action | Tyrosine kinase inhibitor |
|---|
All known targets
- ESR2
- CFTR
- ESRRA
- ESRRB
- ESRRG
- TRPC5
- EGFR
- ESR1
- NCOA1
- NCOA2
- PPARG
- PTK2B
Mechanisms of action (all sources)
- tyrosine kinase inhibitor
- CFTR POTENTIATOR
- ESR2 AGONIST
- ESRRA AGONIST
- ESRRB AGONIST
- ESRRG AGONIST
- TAS2R14 AGONIST
- TAS2R39 AGONIST
- TRPC5 MODULATOR
- ESR2 MODULATOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- HTR2C
- PSMB5
- AR
- SYK
- SLCO2B1
- SLCO1B3
- SLCO1B1
- SLC2A1
- MAOA
- PIM2
- TBXAS1
- DPP4
- NR3C1
- HDAC6
- MGAM
- HSD17B1
- HTR2A
- MAP2K4
- AOX1
- CLK1
- MAOB
- AKR1B1
- TTR
- ADORA2A
- ABCG2
- ABL1
- AKR1B10
- XDH
- PIM3
- OXSR1
- NR1H2
- NR1H3
- NR1H4
- PKM
- ODC1
- OPRD1
- OPRK1
- OPRM1
- VRK1
- VIPR1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- 5HT2A
- NF2L2
- TPO
- SYUA
- SNCA
- SMN
- SMCA2
- RARA
- PRKN
- PRGR
- PHGDH
- NTMT1
- NTM1A
- NSD2
- NR1I2
- NR0B1
- KSYK
- ANDR
- ITPKC
- IFNB1
- HLAB
- HDAC9
- GLI3
- GEM
- GCR
- ERR3
- CREB1
- CP3A7
- CP3A4
- CP2CJ
- CP2C9
- CP1A2
- YAP1
Drug classes
- Anticarcinogenic Agents
- Phytoestrogens
- Protein Kinase Inhibitors
Cross-references
Synonyms
- Genisteine
- Genisteina
- Sparteine l-.alpha.-isosparteine
- (-)-.alpha.-isosparteine
- .alpha.-isospartein
- .alpha.-isosparteine
- .alpha.-isosparteine, (-)-
- .alpha.-sparteine
- 11-isosparteine
- 4',5,7-trihydroxyisoflavone
- Genisteine-alkaloid
- Isosparteine, alpha-
- Sophoricol
- BIO-300
- FW-635I-2
- NPI-031L
- NSC-36586
- NSC-366737
- SIPI-807-1
- Bonistein
- Radioprotective therapy, Humanetics
- GEN
- Genestein
- Genisteol
- Genisterin
- Prunetol
- Differenol A
- G 6649
- G10000
- IN1327
- NPI 031L
- STO514
- TNP00151
- GENISTEIN (ENDOCRINE DISRUPTER)
- Lactoferrin-genistein
- PTI G4660 (Genistein)
- PTI-G4660
- SIPI 807-1
- C.I. 75610
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