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BUTALBITAL
SynDRA canonical compound SYN0000199 — structure-anchored drug synonym record
| Clinical phase | Launched |
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| Approval status | Approved · Rx/OTC |
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| Primary target(s) | GABRQ |
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| Mechanism of action | GABA receptor antagonist |
|---|
| Indication | headache | muscle relaxant |
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| Disease area | neurology/psychiatry |
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All known targets
- GABRA1
- GABRB3
- GABRG2
- GABRB2
- GABRG3
- GABRG1
- GABRE
- GABRD
- GABRB1
- GABRQ
- GABRA6
- GABRA5
Mechanisms of action (all sources)
- GABA receptor antagonist
- GABRA1 POSITIVE ALLOSTERIC MODULATOR
- GABRB2 POSITIVE ALLOSTERIC MODULATOR
- GABRG2 POSITIVE ALLOSTERIC MODULATOR
- GABRB3 POSITIVE ALLOSTERIC MODULATOR
- GABRA4 POSITIVE ALLOSTERIC MODULATOR
- GABRG3 POSITIVE ALLOSTERIC MODULATOR
- GABRQ POSITIVE ALLOSTERIC MODULATOR
- GABRA3 POSITIVE ALLOSTERIC MODULATOR
- GABRP POSITIVE ALLOSTERIC MODULATOR
- GABRD POSITIVE ALLOSTERIC MODULATOR
- GABRG1 POSITIVE ALLOSTERIC MODULATOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ADORA1
- ADORA2A
- HTR2B
- HTR2C
- HTR3A
- KCNH2
- MAOA
- MC3R
- MC4R
- MLNR
- NPY1R
- NR1I2
- NR3C1
- OPRD1
- OPRK1
- OPRM1
- PDE3A
- PDE4D
- PGR
- PTGS2
- SAMHD1
- SLC29A1
- SLC6A2
- SLC6A3
- SLC6A4
- HTR2A
- HTR1A
- HRH2
- BDKRB2
- ADORA3
- ADRA1A
- ADRA2A
- ADRA2B
- ADRA2C
- ADRB1
- ADRB2
- AGTR1
- AVPR1A
- AVPR2
- CCKAR
Drug classes
Cross-references
Synonyms
- ALLZITAL
- ANOQUAN
- AXOTAL
- Allzital
- BANCAP
- BUCET
- BUTALBITAL AND ACETAMINOPHEN
- BUTALBITAL, ACETAMINOPHEN AND CAFFEINE
- BUTALBITAL, ACETAMINOPHEN, CAFFEINE AND CODEINE PHOSPHATE
- BUTALBITAL, ASPIRIN AND CAFFEINE
- BUTALBITAL, ASPIRIN, CAFFEINE, AND CODEINE PHOSPHATE
- BUTAPAP
- alisobumal
- allylbarbital
- allylbarbitone
- allylisobutylbarbital
- allylisobutylbarbituric acid
- butalbarbital
- isobutylallylbarbituric acid
- itobarbital
- Alisobumal
- Allylbarbituric acid
- Itobarbital
- Tetrallobarbital
- Butalbital component of anoquan
- Butalbital component of axotal
- Butalbital component of bancap
- Butalbital component of bucet
- Butalbital component of butapap
- Butalbital component of esgic
- Butalbital component of femcet
- Butalbital component of fioricet
- Butalbital component of fiorinal
- Butalbital component of lanorinal
- Butalbital component of phrenilin
- Butalbital component of sedapap
- Butalbital component of tencon
- Butalbital component of triad
Reported adverse events
- Hepatotoxicity
- Acetaminophen
- Addiction
- Caffeine
- Depression
- Accident
- P
- Androgen deficiency
- Dependence
- Hypotension
- Seizure
- Serotonin syndrome
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