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SULFISOXAZOLE
SynDRA canonical compound SYN0000196 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · OTC |
|---|
| Mechanism of action | bacterial antifolate |
|---|
| Indication | urinary tract infections |
|---|
| Disease area | infectious disease |
|---|
All known targets
- Bact folP
- EDNRA
- EDNRB
- Ednra
- HRH4
- folP
Mechanisms of action (all sources)
- bacterial antifolate
- Bact folP INHIBITOR
- folP INHIBITOR
- folic acid antagonist
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ESR1
- ACHE
- MAPK1
- NR1I2
- NR1H4
- NPY2R
- NPY1R
- MMP9
- MMP1
- MLNR
- MC5R
- MC4R
- MC3R
- MAPK3
- MAPK14
- MAOB
- HMGCR
- MAOA
- LCK
- KCNH2
- HTR6
- HTR3A
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- HRH3
- HRH2
- NR3C1
- OPRD1
- OPRK1
- OPRM1
- TSHR
- THRB
- TDP1
- TBXAS1
- TBXA2R
- TACR2
- TACR1
- SLCO1B3
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
- Sulfonamide Antimicrobial
- Anti-Bacterial Agents
- Anti-Infective Agents
- Antiparasitic Agents
- Antiprotozoal Agents
- Coccidiostats
ATC classes
- J01E · SULFONAMIDES AND TRIMETHOPRIM
- S01A · ANTIINFECTIVES
Cross-references
Synonyms
- AZO GANTRISIN
- GANTRISIN
- SOSOL
- SOXAZOLE
- SULFALAR
- SULFISOXAZOLE DIOLAMINE
- SULSOXIN
- sulfafurazole
- sulfafurazole diolamine
- alphazole
- soxomide
- sulfadimethylisoxazole
- sulfafurazol
- sulfaisoxazole
- sulfazin
- sulfisoxazol
- sulfisoxazole dialamine
- sulphafurazole
- sulfisoxazole diolamine
- Sulfafurazole
- Sulphafurazole
- Sulfafurazol
- Eryzole
- Pediazole
- NSC-13120
- NSC-683536
- Entusil
- Gantrisin
- Neazolin
- Sosol
- Soxazole
- Sulfalar
- Sulfisoxazole component of azo gantrisin
- Sulsoxin
- Accuzole
- Alphazole
- Amidoxal
Reported adverse events
- Angioedema
- Cough
- Crystalluria
- Headache
- Hepatitis
- Leukopenia
- Pseudomembranous colitis
- Stevens-Johnson syndrome
- Tachycardia
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