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CLONAZEPAM
SynDRA canonical compound SYN0000195 — structure-anchored drug synonym record
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | GABRQ |
|---|
| Mechanism of action | GABA benzodiazepine site receptor agonist |
|---|
All known targets
- GABRA1
- GABRA3
- GABRA2
- GABRD
- GABRQ
- GABRP
- GABRG3
- GABRG2
- GABRE
- GABRG1
- GABRB3
- GABRB2
Mechanisms of action (all sources)
- GABA benzodiazepine site receptor agonist
- GABRA1 POSITIVE ALLOSTERIC MODULATOR
- GABRB2 POSITIVE ALLOSTERIC MODULATOR
- GABRG2 POSITIVE ALLOSTERIC MODULATOR
- GABRB3 POSITIVE ALLOSTERIC MODULATOR
- GABRA4 POSITIVE ALLOSTERIC MODULATOR
- GABRG3 POSITIVE ALLOSTERIC MODULATOR
- GABRQ POSITIVE ALLOSTERIC MODULATOR
- GABRA3 POSITIVE ALLOSTERIC MODULATOR
- GABRP POSITIVE ALLOSTERIC MODULATOR
- GABRD POSITIVE ALLOSTERIC MODULATOR
- GABRG1 POSITIVE ALLOSTERIC MODULATOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ACHE
- MMP1
- MC5R
- MC4R
- MC3R
- MAPK3
- MAPK14
- MAPK1
- MAOA
- LCK
- KCNH2
- HTR6
- HTR3A
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- HRH3
- HRH2
- HRH1
- HMGCR
- HCAR2
- GIPR
- GHSR
- GCGR
- FYN
- FLT1
- MLNR
- MMP9
- ADORA1
- NPY1R
- TBXAS1
- TBXA2R
- TACR2
- TACR1
- SLC6A4
- SLC6A3
- SLC6A2
- SLC29A1
- SIGMAR1
Drug classes
- Anticonvulsants
- Central Nervous System Agents
- GABA Agents
- GABA Modulators
- Neurotransmitter Agents
- Benzodiazepine
ATC classes
Cross-references
Synonyms
- KLONOPIN
- KLONOPIN RAPIDLY DISINTEGRATING
- Klonopin
- lonazep
- klonopin
- Ravotril
- Rivatril
- NSC-179913
- RO-5-4023
- RO-54023
- Klonopin rapidly disintegrating
- Rivotril
- Clonazepam civ
- Antelepsin
- Antilepsin
- Chlonazepam
- Cloazepam
- Clonazepamum
- Clonex
- Clonopin
- Iktorivil
- Kenoket
- Landsen
- Lktorivil
- Lonazep
- Melzap
- Paxam
- Rivoril
- Solfidin
- Klonopin Rapidly Disintegrating
- DF2374250
- RO4023
- Ro 4023
- Ro 54023
- Alti-Clonazepam
- Clonazepamum [INN-Latin]
- Klonopin (TN)
Reported adverse events
- Depression
- Fatigue
- Somnolence
- Dysuria
- Ataxia
- Constipation
- Dizziness
- Dysarthria
- Nervousness
- Dehydration
- Hepatomegaly
- Palpitations
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