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SULFAMETHOXAZOLE
SynDRA canonical compound SYN0000173 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Mechanism of action | PABA antagonist |
|---|
| Indication | enteritis | pneumonia | urinary tract infections |
|---|
| Disease area | gastroenterology | infectious disease |
|---|
All known targets
- Bact folP
- Ednra
- folC
- folP
- pol
Mechanisms of action (all sources)
- PABA antagonist
- Bact folP INHIBITOR
- folP INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ACHE
- NPY1R
- MMP1
- MLNR
- MC5R
- MC4R
- MC3R
- MAPT
- MAPK3
- MAPK14
- MAPK1
- MAOA
- LCK
- KCNH2
- HTR6
- HTR3A
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- HRH3
- HRH2
- HRH1
- HMGCR
- HDAC6
- HCAR2
- GMNN
- GIPR
- GHSR
- MMP9
- NPY2R
- ADORA1
- NR3C1
- USP2
- TBXAS1
- TBXA2R
- TACR2
- TACR1
- SLCO1B3
- SLCO1B1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
- Sulfonamide Antimicrobial
- Anti-Infective Agents
- Cytochrome P450 2C9 Inhibitors
ATC classes
- J01E · SULFONAMIDES AND TRIMETHOPRIM
- DRUGS FOR TREATMENT OF TUBERCULOSIS
Cross-references
Synonyms
- AZO GANTANOL
- BACTRIM
- BACTRIM DS
- BACTRIM PEDIATRIC
- COTRIM
- COTRIM D.S.
- GANTANOL
- GANTANOL-DS
- SEPTRA
- SEPTRA DS
- SEPTRA GRAPE
- SULFAMETHOPRIM
- sulfamethalazole
- sulfamethoxazol
- sulfisomezole
- sulphamethoxazole
- Sulfametoxazol
- Acetylsulfamethoxazole
- Sulfamethoxazole sodium
- Sulfamethoxazolum
- Sulphamethoxazole
- NSC-147832
- RO-4-2130
- STX-608
- Gantanol
- Gantanol-ds
- Sinomin
- Sulfamethoxazole component of azo gantanol
- Sulfamethoxazole component of bactrim
- Sulfamethoxazole component of bactrim ds
- Sulfamethoxazole component of bactrim pediatric
- Sulfamethoxazole component of co-trimethoxazole
- Sulfamethoxazole component of cotrim
- Sulfamethoxazole component of cotrim d.s.
- Sulfamethoxazole component of septra
- Sulfamethoxazole component of sulfamethoprim
- Sulfamethoxazole component of sulfatrim
- Sulfamethoxazole component of sulmeprim
Reported adverse events
- Stevens-Johnson syndrome
- Agranulocytosis
- Hallucination
- Cough
- Arthralgia
- Hepatitis
- Renal failure
- Pneumonia
- Thrombocytopenia
- Hypersensitivity
- Uveitis
- Local reaction
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