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SEROTONIN
SynDRA canonical compound SYN0000164 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Primary target(s) | HTR3B |
|---|
| Mechanism of action | Growth factor receptor activator |
|---|
| Indication | anxiety | depression | sleeplessness |
|---|
| Disease area | neurology/psychiatry |
|---|
All known targets
- HTR2B
- HTR3B
- HTR7
- HTR1A
- HTR1B
- HTR1D
- HTR6
- HTR5A
- HTR2A
- HTR4
- HTR2C
- HTR3A
Mechanisms of action (all sources)
- Growth factor receptor activator
- HTR1A FULL AGONIST
- HTR1B FULL AGONIST
- HTR1D FULL AGONIST
- HTR1E FULL AGONIST
- HTR1F FULL AGONIST
- HTR2A FULL AGONIST
- HTR2B FULL AGONIST
- HTR2C FULL AGONIST
- HTR3A AGONIST
- HTR3B AGONIST
- HTR4 FULL AGONIST
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- CA4
- CA12
- SLC18A2
- CA7
- CA5B
- CA5A
- DRD3
- CA3
- CA14
- DRD2
- MARK4
- NTHL1
- POU2F2
- SLC22A2
- SAMHD1
- S1PR1
- RGS4
- RECQL
- POU2F1
- OGG1
- MTNR1B
- OPRM1
- MUTYH
- NEIL1
- NEIL2
- NPSR1
- ACHE
- SLC47A2
- SLC22A3
- SLC47A1
- UGT2B7
- UGT2B4
- UGT2B17
- UGT2B15
- UGT1A6
- UGT1A4
- UGT1A1
- TYR
- TSHR
- TRPM8
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- 5HT1A
- 5HT6R
- HTR3E
- HTR3D
- HTR3C
- G3P
- CP1A2
- ALR
- 5HT7R
- 5HT5A
- 5HT1B
- 5HT4R
- 5HT2C
- 5HT2B
- 5HT2A
- 5HT1F
- 5HT1E
- 5HT1D
- MDR1
Drug classes
- Serotonin Receptor Agonists
Cross-references
Synonyms
- 5-ht
- 5-hydroxytryptamine
- Enteramine
- Thrombotonin
- 5-HYDROXYTRYPTAMINE
- 3-(2-Aminoethyl)-1H-indol-5-ol
- 5-HT
- Serotonine
- Thrombocytin
- Antemovis
- Ds substance
- Hippophain
- Antemoqua
- Substance DS
- Substanz DS
- 1H-Indol-5-ol, 3-(2-aminoethyl)-
- 5-Hta
- Tryptamine, 5-hydroxy-
- 3-(2-Aminoethyl)indol-5-ol
- Enteramin
- UNII-333DO1RDJY
- Indol-5-ol, 3-(2-aminoethyl)-
- 5-Hydroxy-3-(beta-aminoethyl)indole
- 3-(beta-Aminoethyl)-5-hydroxyindole
- EINECS 200-058-9
- 3-(2-Amino-ethyl)-1H-indol-5-ol
- BRN 0143524
- 333DO1RDJY
- CHEBI:28790
- 5 Hydroxytryptamine
- Hippophaine
- 3-(2-Aminoethyl)-1H-indol-5-o
- Serotonin (Human)
- Serotonin 1543
- RefChem:6493
- DTXCID4040765
- NSC58241
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