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5-METHOXYTRYPTAMINE
SynDRA canonical compound SYN0000161 — structure-anchored drug synonym record
| Primary target(s) | HTR6 |
|---|
| Mechanism of action | Serotonin receptor agonist |
|---|
All known targets
- HTR2A
- HTR6
- HTR1B
- HTR1D
- HTR1E
- HTR1F
- HTR2C
- HTR4
- HTR7
- TRPM8
Mechanisms of action (all sources)
- Serotonin receptor agonist
- HTR1B FULL AGONIST
- HTR1D FULL AGONIST
- HTR1E FULL AGONIST
- HTR1F FULL AGONIST
- HTR2A FULL AGONIST
- HTR2C FULL AGONIST
- HTR4 FULL AGONIST
- HTR6 FULL AGONIST
- HTR7 FULL AGONIST
- HTR6 INHIBITOR
- HTR2A INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- HTR1A
- ACHE
- NFKB1
- TDP1
- SLCO1B3
- SLCO1B1
- SLC47A2
- SLC47A1
- SLC22A3
- POU2F2
- POU2F1
- POLI
- PMP22
- NPSR1
- MPHOSPH8
- BAZ2B
- MAPT
- KDM4A
- EHMT2
- DRD1
- CYP3A4
- CYP2D6
- CYP2C9
- CYP2C19
- CYP1A2
- BLM
- TSHR
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- 5HT1B
- 5HT1D
- 5HT1E
- 5HT1F
- 5HT2A
- 5HT2C
- 5HT4R
- 5HT5A
- 5HT6R
- 5HT7R
- CP1A2
- DRD2
- M4K2
- TRFR
Cross-references
Synonyms
- 2-(5-Methoxy-1H-indol-3-yl)ethanamine
- Mexamine
- Methoxytryptamine
- 3-(2-Aminoethyl)-5-methoxyindole
- Mexamine base
- 5MOT
- 5-Mot
- 1H-Indole-3-ethanamine, 5-methoxy-
- 2-(5-Methoxyindol-3-yl)ethylamine
- Meksamin
- Meksamin (free base)
- 5-MeOT
- O-Methylserotonin
- 2-(5-Methoxy-1H-Indol-3-Yl)Ethan-1-Amine
- NSC 56422
- 5-MT
- UNII-3VMW6141KC
- INDOLE, 3-(2-AMINOETHYL)-5-METHOXY-
- 5-methoxy-1H-indole-3-ethanamine
- EINECS 210-153-7
- Lopac-M-6628
- 5-Methoxytryptamine, 97%
- BRN 0145587
- CHEMBL8165
- 3VMW6141KC
- CHEBI:2089
- Meksamine
- RefChem:103077
- DTXCID10132129
- o-methyl serotonin
- MFCD00005662
- 5-Methoxytryptamine (5-MT)
- NSC56422
- C05659
- 2-(5-METHOXY-1H-INDOL-3-YL)-ETHYLAMINE
- SMR000112269
- DEACETYLMELATONIN
- 2-(5-Methoxy-1H-indol-3-yl)ethanamine (5-Methoxytryptamine)
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