THIAMYLAL

SynDRA canonical compound SYN0000153 — structure-anchored drug synonym record

Clinical phase	Launched
Approval status	Approved · OTC
Primary target(s)	GABRA1
Mechanism of action	Glutamate receptor antagonist
Indication	sedative
Disease area	neurology/psychiatry

All known targets

GABRA1
GABRG3
GABRA2
GABRA3
GABRA4
GABRA5
GABRA6
GABRB1
GABRB2
GABRB3
GABRD
GABRE

Mechanisms of action (all sources)

Glutamate receptor antagonist
GABRA1 POSITIVE ALLOSTERIC MODULATOR
GABRB2 POSITIVE ALLOSTERIC MODULATOR
GABRG2 POSITIVE ALLOSTERIC MODULATOR
GABRB3 POSITIVE ALLOSTERIC MODULATOR
GABRA4 POSITIVE ALLOSTERIC MODULATOR
GABRG3 POSITIVE ALLOSTERIC MODULATOR
GABRQ POSITIVE ALLOSTERIC MODULATOR
GABRA3 POSITIVE ALLOSTERIC MODULATOR
GABRP POSITIVE ALLOSTERIC MODULATOR
GABRD POSITIVE ALLOSTERIC MODULATOR
GABRG1 POSITIVE ALLOSTERIC MODULATOR

Bioactivity evidence (ChEMBL activities table — not curator-asserted)

NR1I2
CYP3A4
SLCO1B1
SLCO1B3

Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)

CP3A4

Drug classes

Anesthetics
Anesthetics, Intravenous
Central Nervous System Agents
Central Nervous System Depressants
GABA Agents
GABA Modulators
Hypnotics and Sedatives
Neurotransmitter Agents

Cross-references

PubChem CID: 3032285
ChEMBL: CHEMBL440
DrugBank: DB01154
ChEBI: CHEBI:9536
KEGG: D00713
RxNorm: 10464
Wikipedia: Thiamylal
TTD: D06NSA
LINCS BRD: BRD-A23970436

Synonyms

Look up THIAMYLAL in the interactive SynDRA portal →