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ISOPROTERENOL
SynDRA canonical compound SYN0000140 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | ADRB3 |
|---|
| Mechanism of action | Adrenergic receptor agonist |
|---|
| Indication | asthma | bradycardia | heart block |
|---|
| Disease area | cardiology | pulmonary |
|---|
All known targets
- ADRB1
- ADRB2
- ADRB3
- TAS2R42
- TAS2R31
- TAS2R38
- TAS2R39
- TAS2R4
- TAS2R40
- TAS2R41
- TAS2R43
- TAS2R8
Mechanisms of action (all sources)
- Adrenergic receptor agonist
- ADRB1 AGONIST
- Adrenergic receptor beta agonist
- ADRB2 AGONIST
- ADRB3 AGONIST
- ADRB1 FULL AGONIST
- ADRB2 FULL AGONIST
- ADRB3 FULL AGONIST
- ADRB2 MODULATOR
- IL12B MODULATOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ADRA1A
- ADRA1D
- ACHE
- NR1I2
- MMP1
- MMP9
- MTOR
- NFE2L2
- NPY1R
- NPY2R
- NTSR1
- NR3C1
- MC5R
- OPRD1
- OPRK1
- OPRM1
- PDE3A
- PDE4D
- MLNR
- MC4R
- PGR
- MC3R
- MAPT
- MAPK3
- MAPK14
- MAPK1
- MAOA
- LCK
- KDM4E
- KCNH2
- HTR6
- HTR3A
- HTR2C
- HTR2B
- HTR2A
- PDE5A
- PMP22
- HSD17B10
- SLC29A1
- VDR
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ADRA1B
- AHR
- SC5A7
- PE2R2
- MRGPRX1
- KLK7
- GRK2
- GNRHR
- GLI3
- ESRRA
- CREB1
- CP3A7
- CP2D6
- CP2CJ
- CP2C9
- CP1A2
- ALAT2
- TRFR
Drug classes
- Adrenergic beta-Agonists
- beta-Adrenergic Agonist
- Adrenergic Agents
- Adrenergic Agonists
- Anti-Asthmatic Agents
- Bronchodilator Agents
- Cardiotonic Agents
- Cardiovascular Agents
- Neurotransmitter Agents
- Peripheral Nervous System Agents
- Protective Agents
- Respiratory System Agents
ATC classes
- C01C · CARDIAC STIMULANTS EXCL. CARDIAC GLYCOSIDES
- R03C · ADRENERGICS FOR SYSTEMIC USE
- R03A · ADRENERGICS, INHALANTS
Cross-references
Synonyms
- AEROLONE
- DUO-MEDIHALER
- ISOPROTERENOL HYDROCHLORIDE
- ISUPREL
- Isuprel
- MEDIHALER-ISO
- MUCOMYST W/ ISOPROTERENOL
- NORISODRINE
- NORISODRINE AEROTROL
- VAPO-ISO
- isoprenaline
- isoproterenol hydrochloride
- DL-Isoproterenol
- isoprenalin
- isoprenaline sulfate
- DL-isoprenaline hydrochloride
- isoproterenol sulfate
- isoproterenol HCl
- DL-isoprenaline HCl
- Isoprenaline
- Isoprenalina
- Isoproterenol dl-form
- Aleudrin
- Aludrine
- Asiprenol
- Asmalar
- Assiprenol
- Bellasthman
- Isonorin
- Isopropydrin
- Isorenin
- Isupren
- Neo-epinine
- Neodrenal
- Novodrin
- Proternol
- Respifral
- Saventrine
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