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GEMIFLOXACIN
SynDRA canonical compound SYN0000133 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · OTC |
|---|
| Mechanism of action | bacterial DNA gyrase inhibitor |
|---|
| Indication | bronchitis | pneumonia |
|---|
| Disease area | infectious disease | pulmonary |
|---|
All known targets
- Bact gyrA
- Bact gyrB
- Stap-coc parC
- gyrB
- parC
Mechanisms of action (all sources)
- DNA gyrase inhibitor
- Bact gyrA; Bact gyrB MODULATOR
- Stap-coc parC MODULATOR
- parC INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- DRD1
- DPP4
- PTGS1
- LMNA
- MAOA
- OPRM1
- PDE3A
- PDE4A
- PGR
- POLK
- ABCC4
- KDM4E
- SLC6A2
- SLC6A3
- SLC6A4
- SLCO1B1
- SLCO1B3
- TBXA2R
- TDP1
- KDR
- KCNH2
- ACHE
- CHRM2
- ADORA1
- ADORA3
- ADRA1A
- ADRA2A
- AR
- CHRM1
- DRD3
- HTR2B
- ESR1
- F2
- HDAC6
- HRH3
- HSD17B10
- HTR1A
- TOP2A
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
- Anti-Bacterial Agents
- Anti-Infective Agents
- Antineoplastic Agents
- Enzyme Inhibitors
- Topoisomerase II Inhibitors
- Topoisomerase Inhibitors
- Quinolone Antimicrobial
ATC classes
- J01M · QUINOLONE ANTIBACTERIALS
Cross-references
Synonyms
- FACTIVE
- Factive
- GEMIFLOXACIN MESYLATE
- gemifloxacin mesilate
- gemifloxacin mesylate
- Gemifloxacine
- Gemifloxacino
- Factiv
- Gemifloxacin [INN]
- Gemifloxacin mesilate
- LB-20304
- LB 20304a
- SB-265805
- Factiv (TN)
- Factive (TN)
- Gemifloxacin (INN)
- OKR68Y0E4T
- LB 20304
- CHEBI:101853
- LB20304
- Gemifloxacinum
- RefChem:56635
- DTXCID9028469
- J01MA15
- SB265805
- Gemifioxacin
- Gemifloxacin (mesylate)
- UNII-OKR68Y0E4T
- SR-05000001958
- C18H20FN5O4
- HSDB 8027
- SB-265805S;LB-20304a
- GEMIFLOXACIN [MI]
- GEMIFLOXACIN [VANDF]
- BSPBio_002308
- GEMIFLOXACIN [WHO-DD]
- SCHEMBL136633
- orb1705500
Reported adverse events
- Tendinitis
- Peripheral neuropathy
- Rash
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