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GATIFLOXACIN
SynDRA canonical compound SYN0000125 — structure-anchored drug synonym record
| Clinical phase | Withdrawn |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Mechanism of action | bacterial DNA gyrase inhibitor |
|---|
All known targets
- Bact gyrA
- Bact gyrB
- Stap-coc parC
- gyrA
- gyrB
- parC
- parE
Mechanisms of action (all sources)
- DNA gyrase inhibitor
- Bact gyrA; Bact gyrB MODULATOR
- Stap-coc parC MODULATOR
- parC INHIBITOR
- parE INHIBITOR
- gyrB INHIBITOR
- gyrA INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ESR1
- ACHE
- MAOA
- NR1I2
- NPY2R
- NPY1R
- MMP9
- MMP1
- MLNR
- MC5R
- MC4R
- MC3R
- MAPK3
- MAPK14
- MAPK1
- LCK
- HDAC6
- KDM4E
- KCNH2
- HTR6
- HTR3A
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- HSD17B10
- HRH2
- HRH1
- HPGD
- NR3C1
- OPRD1
- OPRK1
- SLC29A1
- VDR
- TOP2A
- TDP1
- TBXAS1
- TBXA2R
- TACR2
- TACR1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- HTT
- ID4
- IFNG
- KPCD3
- KSYK
- SC5A7
- SYK
Drug classes
- Anti-Bacterial Agents
- Anti-Infective Agents
- Antineoplastic Agents
- Enzyme Inhibitors
- Ophthalmic Solutions
- Pharmaceutical Solutions
- Topoisomerase II Inhibitors
- Topoisomerase Inhibitors
- Quinolone Antimicrobial
ATC classes
- S01A · ANTIINFECTIVES
- J01M · QUINOLONE ANTIBACTERIALS
Cross-references
Synonyms
- ZYMAR
- ZYMAXID
- Zymaxid
- gatifloxacin anhydrous
- gatifloxin
- gatifloxacin hydrate
- Gatifloxacine
- Gatifloxacino
- Gatifloxacin hydrate
- Gatifloxacin sesquihydrate
- Gatiflo
- Gatifloxacin (sesquihydrate)
- Gatifloxacin anhydrous
- Zymer
- AM-1155
- BMS-206584-01
- BMS-20658401
- NSC-758701
- PD-135432
- Tequin
- Zymar
- Bonoq
- GTFX
- Gaity
- Gatilox
- Gatiquin
- Gatispan
- CG 5501;PD 135432
- PD135432
- BMS-206584
- CG-5501
- Gatiflo (TN)
- Gatifloxacin & Gamma Interferon
- Gatifloxacin (INN)
- Gatifloxacin (TN)
- Gatifloxacin [USAN:INN]
- Tequin (TN)
Reported adverse events
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