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CIGLITAZONE
SynDRA canonical compound SYN0000115 — structure-anchored drug synonym record
| Clinical phase | Phase 2 |
|---|
| Primary target(s) | PPARG |
|---|
| Mechanism of action | PPAR receptor agonist |
|---|
All known targets
Mechanisms of action (all sources)
- PPAR receptor agonist
- PPARG FULL AGONIST
- PPARG AGONIST
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- CA2
- SLC6A4
- NR1I2
- DRD1
- DRD2
- CHRM4
- CHRM3
- CHRM2
- DRD3
- EGFR
- ESR2
- SLC6A2
- OPRD1
- HPGD
- ADRA2B
- ADORA3
- TACR2
- ADRA2A
- MAOB
- KAT2A
- NR1H4
- NPY2R
- NPY1R
- NFE2L2
- KCNH2
- LCK
- MAPK1
- MMP9
- MMP1
- MC5R
- MC4R
- MC3R
- NR3C1
- MAOA
- MAPK3
- MAPK14
- ABCB11
- PPARD
- OPRK1
- RPS6KB1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- CP19A
- CP2CJ
- CP3A4
- CP3A7
- NF2L2
- RAPGEF3
- RAPGEF4
- RARA
- RPGF3
- RPGF4
- UBP1
Drug classes
Cross-references
Synonyms
- Ciglitazona
- ADD-3878
- U-63,287
- U-63287
- Ciglitizone
- ADD 3878
- Ciglitazonum
- Ciglitazonum [Latin]
- Ciglitazona [Spanish]
- Ciglitazone [USAN:INN]
- CHEBI:64227
- U 63287
- (+-)-5-(p-((1-Methylcyclohexyl)methoxy)benzyl)-2,4-thiazolidinedione
- C18H23NO3S
- 5-(4-((1-methylcyclohexyl)methoxy)benzyl)thiazolidine-2,4-dione
- YZFWTZACSRHJQD-UHFFFAOYSA-N
- (+/-)-5-[4-(1-Methylcyclohexylmethoxy)benzyl]thiazolidine-2,4-dione
- 5-{4-[(1-methylcyclohexyl)methoxy]benzyl}-1,3-thiazolidine-2,4-dione
- NCGC00164446-01
- U8QXS1WU8G
- DTXCID8020757
- RefChem:577129
- MFCD00865499
- CAS-74772-77-3
- SR-01000597400
- UNII-U8QXS1WU8G
- Spectrum5_001949
- CIGLITAZONE [INN]
- Ciglitazone (USAN/INN)
- CIGLITAZONE [USAN]
- UPCMLD-DP145
- CBiol_001858
- SCHEMBL38185
- BSPBio_001575
- KBioGR_000295
- KBioSS_000295
- BML2-F01
- GTPL2711
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