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SALICYLIC ACID
SynDRA canonical compound SYN0000103 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | PTGS1 |
|---|
| Mechanism of action | Prostanoid receptor antagonist |
|---|
| Indication | diarrhea |
|---|
| Disease area | gastroenterology |
|---|
All known targets
- PTGS1
- PTGS2
- CA1
- CA12
- CA2
- CA4
- CA6
- ASIC3
- AKR1C1
- HMGB1
- SABP2
- PPO2
Mechanisms of action (all sources)
- Cyclooxygenase inhibitor
- Prostanoid receptor inhibitor
- Prostanoid receptor antagonist
- PTGS2 INHIBITOR
- PTGS1 INHIBITOR
- ASIC3 MODULATOR
- beta-secretase inhibitor
- CA6 INHIBITOR
- CA12 INHIBITOR
- CA2 INHIBITOR
- CA4 INHIBITOR
- CA1 INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ABCB1
- HPGD
- NR3C1
- NPY2R
- NPY1R
- MMP9
- MMP8
- MMP3
- MMP2
- MMP1
- MC5R
- MC4R
- MC3R
- MAPK3
- MAPK14
- MAPK1
- MAOA
- LMNA
- LCK
- KDM4E
- KCNH2
- KAT2A
- IKBKB
- IDO1
- HTR6
- HTR2C
- HTR2B
- HTR2A
- HRH2
- OPRD1
- OPRK1
- OPRM1
- SLC6A4
- UGT2B4
- UGT2B10
- UGT1A9
- TDP1
- TBXAS1
- TACR2
- TACR1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
- Antidiarrheals
- Gastrointestinal Agents
- Analgesics
- Analgesics, Non-Narcotic
- Anti-Inflammatory Agents
- Anti-Inflammatory Agents, Non-Steroidal
- Antirheumatic Agents
- Cyclooxygenase Inhibitors
- Enzyme Inhibitors
- Peripheral Nervous System Agents
- Sensory System Agents
- Bismuth
ATC classes
- N02B · OTHER ANALGESICS AND ANTIPYRETICS
- S01B · ANTIINFLAMMATORY AGENTS
- D01A · ANTIFUNGALS FOR TOPICAL USE
Cross-references
Synonyms
- AcneWorx
- Acneclir
- BISMUTH SUBSALICYLATE, METRONIDAZOLE AND TETRACYCLINE HYDROCHLORIDE
- Backprin
- Bismusal
- Broda Acne Spa
- Clearskin Pore Penetrating Black Mineral Mask
- Clearskin Professional Daily Correcting
- Cornstick
- Dermoneen
- Doans
- Duofilm
- choline salicylate
- choline subsalicylate
- 2-Carboxyphenol
- 2-Hydroxybenzenecarboxylic acid
- 2-Hydroxybenzoic acid
- imidazole salicylate
- sodium salicylate
- morpholine salicylate
- potassium salicylate
- bismuth subsalicylate
- bismogenol
- bismuth oxysalicylate
- 2-hydroxybenzoic acid
- FEMA NO. 3985
- K-557
- NSC-180
- Acnisal
- Bazuka
- Compound v
- Compound w
- Cuplex verruca
- Dr. scholl's callus removers
- Edinburgh
- Erytex
- Gppe paint
- Jadit
Reported adverse events
- Hypersensitivity
- Asthenia
- Dysuria
- Erythema
- Insomnia
- Constipation
- Dizziness
- Dyspareunia
- Flatulence
- Henoch-Schonlein purpura
- Hepatotoxicity
- Pancreatitis
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