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SULPIRIDE
SynDRA canonical compound SYN0000100 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Primary target(s) | CA7 |
|---|
| Mechanism of action | Dopamine receptor antagonist |
|---|
| Indication | schizophrenia |
|---|
| Disease area | neurology/psychiatry |
|---|
All known targets
- DRD2
- CA7
- DRD3
- DRD4
- CA1
- CA12
- mtcA1
- cynT
- ca1
- NCE103
- Drd5
- Drd4
Mechanisms of action (all sources)
- Dopamine receptor antagonist
- DRD2 ANTAGONIST
- Dopamine D2 receptor antagonist
- CA1 INHIBITOR
- CA12 INHIBITOR
- CA7 INHIBITOR
- DRD3 ANTAGONIST
- DRD4 ANTAGONIST
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- KCNH2
- ACHE
- MAPK1
- NR3C1
- NPY2R
- NPY1R
- MMP9
- MMP1
- MC5R
- MC4R
- MC3R
- MAPT
- MAPK3
- MAPK14
- MAOA
- ADORA1
- LCK
- KDR
- KAT2A
- HTR7
- HTR6
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- HSPA5
- OPRD1
- OPRK1
- OPRM1
- PDE3A
- TBXAS1
- TBXA2R
- TACR2
- TACR1
- SLCO1B3
- SLCO1B1
- SLC6A4
- SLC6A3
- SLC6A2
- SLC47A2
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- CAH12
- CAH7
- CP2D6
- CYP21A2
- NTM1A
- RXRA
Drug classes
- Antidepressive Agents
- Antidepressive Agents, Second-Generation
- Antipsychotic Agents
- Central Nervous System Agents
- Central Nervous System Depressants
- Dopamine Agents
- Dopamine Antagonists
- Neurotransmitter Agents
- Psychotropic Drugs
- Tranquilizing Agents
ATC classes
Cross-references
Synonyms
- sulpirid
- sulpitil
- sulpyrid
- sursumid
- Sulpirida
- N05AL01
- NSC-757850
- RD-1403
- Abilit
- Aiglonyl
- Coolspan
- Dobren
- Dogmatil
- Dogmatyl
- Dolmatil
- Guastil
- Meresa
- Mirbanil
- Misulvan
- Neogama
- Omperan
- Pyrikappl
- Sernevin
- Splotin
- Sulpitil
- Sulpor
- Sursumid
- Synedil
- Trilan
- Alimoral
- Arminol
- Calmoflorine
- Championyl
- Darleton
- Deponerton
- Desisulpid
- Desmenat
- Digton
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