COUMARIN

SynDRA canonical compound SYN0000092 — structure-anchored drug synonym record

Clinical phase	Launched
Primary target(s)	CA1 \| CA12 \| CA14 \| CA2 \| CA4 \| CA6 \| CA9 \| CYP2A6
Mechanism of action	vitamin K antagonist
Indication	asthma \| celiac disease \| ulcerative colitis
Disease area	gastroenterology \| pulmonary

All known targets

CA1
CA4
CA9
CA12
CA6
CA2
CA14
CA3
CA5A
CA5B
CA7
CYP2A6

Mechanisms of action (all sources)

vitamin K antagonist
CA4 INHIBITOR
CA1 INHIBITOR
CA6 INHIBITOR
CA9 INHIBITOR
CA14 INHIBITOR
CA2 INHIBITOR
CA12 INHIBITOR

Bioactivity evidence (ChEMBL activities table — not curator-asserted)

Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)

CP1A2
NF2L2
NR1I2
TP53

Cross-references

PubChem CID: 323
ChEMBL: CHEMBL6466
DrugBank: DB04665
ChEBI: CHEBI:28794
KEGG: D07751
RxNorm: 2898
PDB: COU
Wikipedia: Coumarin
TTD: D03ZMQ
LINCS BRD: BRD-K23913458

Synonyms

Look up COUMARIN in the interactive SynDRA portal →