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EPIRUBICIN
SynDRA canonical compound SYN0000081 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | TOP2A |
|---|
| Mechanism of action | Topoisomerase inhibitor |
|---|
| Indication | breast cancer |
|---|
| Disease area | oncology |
|---|
All known targets
- TOP2A
- CHD1
- FYN
- HTR4
- NS3
- TOP2B
Mechanisms of action (all sources)
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- TBXA2R
- ADRA1A
- PTGS1
- ABCC1
- MC4R
- MC5R
- MMP1
- MMP9
- NFE2L2
- NPY1R
- MAPK3
- NPY2R
- NR3C1
- OPRD1
- OPRK1
- OPRM1
- MC3R
- MAPK14
- PDE4A
- MAPK1
- MAOA
- LCK
- KDM4A
- KCNH2
- IDH1
- HTR6
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- HRH3
- PDE3A
- PGR
- PDE5A
- SLC6A3
- VIPR1
- USP1
- UGT2B7
- TSG101
- TDP1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- APAF
- NR5A2
- OXYR
- PA1B2
- PA1B3
- PADI4
- PAFA
- PAFA2
- PARP1
- PPME1
- RAD51
- SENP8
- SUMO1
- SYK
- TNNC1
- TNNI3
- TNNT2
- TR10B
- UBP1
- NSD2
- MITF
- B2CL1
- MDM4
- CAC1H
- CFTR
- CGAS
- CRHBP
- CRHR2
- GSTO1
- HCRTR1
- HLAB
- HSF1
- IDHC
- IFNB1
- IFNG
- KSYK
- LYPA1
- M4K2
- MCL1
- MDM2
Drug classes
- Topoisomerase Inhibitors
- Anthracycline Topoisomerase Inhibitor
- Antibiotics, Antineoplastic
- Antineoplastic Agents
- Enzyme Inhibitors
- Topoisomerase II Inhibitors
ATC classes
- L01D · CYTOTOXIC ANTIBIOTICS AND RELATED SUBSTANCES
Cross-references
Synonyms
- ELLENCE
- EPIRUBICIN HYDROCHLORIDE
- Ellence
- epiadriamycin
- epidoxorubicin
- epirarubicin
- farmarubicin
- farmarubicine
- pharmarubicin
- epirubicin hydrochloride
- epirubicin HCl
- Epirubicine
- Epirubicina
- 4'-epi-adriamycin
- Epiadriamycin
- Epidoxorubicin
- Farmorubicin
- NSC-256942
- Epirubicinum
- Pidorubicin
- Pidorubicina
- Pidorubicine
- Pidorubicinum
- Ridorubicin
- Epirubicina [Spanish]
- Epirubicine [French]
- Epirubicinum [Latin]
- Pharmorubicin Pfs
- IMI 28
- WP 697
- Ebewe (TN)
- Ellence (TN)
- Epi-DX
- Epirubicin (INN)
- Epirubicin (TN)
- Epirubicin [INN:BAN]
- Epirubicina [INN-Spanish]
- Epirubicine [INN-French]
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