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DICHLORPHENAMIDE
SynDRA canonical compound SYN0000078 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | CA12 |
|---|
| Mechanism of action | Carbonic anhydrase inhibitor |
|---|
| Indication | epilepsy | glaucoma |
|---|
| Disease area | neurology/psychiatry | ophthalmology |
|---|
All known targets
- CA12
- CA2
- CA4
- CA1
- CA7
- CA
- CYP2C9
- mtcA1
- cynT
- ca1
- NCE103
- Ca15
Mechanisms of action (all sources)
- Carbonic anhydrase inhibitor
- CA1 INHIBITOR
- Carbonic anhydrase I inhibitor
- CA2 INHIBITOR
- Carbonic anhydrase II inhibitor
- CA12 INHIBITOR
- Carbonic anhydrase XII inhibitor
- CA4 INHIBITOR
- Carbonic anhydrase IV inhibitor
- CYP21A2 INHIBITOR
- CA1 MODULATOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- CA3
- ADORA1
- NR1I2
- HTR1A
- HTR2A
- HTR2B
- HTR2C
- HTR3A
- KCNH2
- LMNA
- MAOA
- MAOB
- MC3R
- MC4R
- MLNR
- NPY1R
- NR3C1
- HRH2
- OPRD1
- OPRK1
- OPRM1
- PDE3A
- PDE4D
- PGR
- PTGS2
- SAMHD1
- SLC29A1
- SLC6A2
- SLC6A3
- SLC6A4
- TBXA2R
- HRH3
- HRH1
- ADORA2A
- CHRM1
- ADORA3
- ADRA1A
- ADRA2A
- ADRA2B
- ADRA2C
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
- Carbonic Anhydrase Inhibitors
- Carbonic Anhydrase Inhibitor
- Enzyme Inhibitors
ATC classes
- S01E · ANTIGLAUCOMA PREPARATIONS AND MIOTICS
Cross-references
Synonyms
- DARANIDE
- KEVEYIS
- Keveyis
- ORMALVI
- Ormalvi
- diclofenamide
- dichlofenamide
- dichlorophenamide
- diclofenamid
- Diclofenamide
- Diclofenamida
- Daranide
- Oratrol
- 4,5-dichlorobenzene-1,3-disulfonamide
- Dichlofenamide
- Dichlorophenamide
- Dichlorphenamid
- Glauconide
- Antidrasi
- Glaucol
- Diclofenamidum
- Diclofenamid
- Barastonin
- Glaumid
- Glafco
- Glajust
- 4,5-Dichloro-m-benzenedisulfonamide
- 1,3-Benzenedisulfonamide, 4,5-dichloro-
- Diclofenamidum [INN-Latin]
- 4,5-Dichloro-1,3-disulfamoylbenzene
- 1,3-Disulfamoyl-4,5-dichlorobenzene
- Diclofenamida [INN-Spanish]
- 1,3-Disulfamyl-4,5-dichlorobenzene
- Dasanide
- Dichlorphenamide [BAN]
- Llorens Brand of Dichlorphenamide
- Merck Brand of Dichlorphenamide
Reported adverse events
- Fall
- Hypersensitivity
- Cognitive disorder
- Arthralgia
- Confusional state
- Dizziness
- Dysgeusia
- Fatigue
- Headache
- Lethargy
- Malaise
- Muscle spasms
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