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DEPHOSTATIN
SynDRA canonical compound SYN0000073 — structure-anchored drug synonym record
| Primary target(s) | PTPN6 |
|---|
| Mechanism of action | Tyrosine phosphatase inhibitor |
|---|
All known targets
Mechanisms of action (all sources)
- Tyrosine phosphatase inhibitor
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ALDH1A1
- POLI
- MPHOSPH8
- MTOR
- NFE2L2
- NFKB1
- PIN1
- PKM
- PMP22
- POLB
- POLH
- POLK
- MAPT
- RECQL
- RGS12
- RGS4
- SMAD3
- SNCA
- TDP1
- THPO
- THRB
- USP2
- MBNL1
- LMNA
- ALOX15
- CYP2C19
- APEX1
- APP
- ARSA
- ATXN2
- BLM
- BRCA1
- CASP1
- CBX1
- CYP1A2
- CYP2C9
- KDM4A
- CYP2D6
- CYP3A4
- EHMT2
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ADCY9
- AICDA
- THB
- RUNX1
- PNMT
- PHGDH
- PEBB
- NTM1A
- NNMT
- MITF
- LOX15
- HS90B
- HS90A
- HNMT
- GNMT
- GNAI1
- GLSK
- GAMT
- FUMH
- ESR1
- DPOLB
- CP1A2
- COMT
- UBP2
Cross-references
Synonyms
- 1,4-Benzenediol, 2-(methylnitrosoamino)-
- N-(2,5-dihydroxyphenyl)-N-methylnitrous amide
- RefChem:132022
- 2-(Methylnitrosoamino)-1,4-benzenediol
- Lopac-D-8065
- Lopac0_000403
- orb3024278
- SCHEMBL3893046
- SCHEMBL12305062
- CHEBI:202847
- HMS3261A08
- 2-(N-methyl-N-nitroso)hydroquinone
- Tox21_500403
- HSCI1_000163
- HY-N15015
- AKOS006271953
- CCG-204496
- LP00403
- SDCCGSBI-0050389.P002
- TN10643
- NCGC00015372-01
- NCGC00015372-02
- NCGC00015372-03
- NCGC00015372-04
- NCGC00093830-01
- NCGC00093830-02
- NCGC00261088-01
- D8065
- EU-0100403
- D 8065
- SR-01000075834
- SR-01000075834-1
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