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DIETHYLSTILBESTROL
SynDRA canonical compound SYN0000061 — structure-anchored drug synonym record
| Clinical phase | Withdrawn |
|---|
| Approval status | Approved · OTC |
|---|
| Primary target(s) | ESR1 | ESR2 | ESRRB | ESRRG |
|---|
| Mechanism of action | estrogen receptor agonist |
|---|
All known targets
- ESR1
- ESRRB
- ESR2
- ESRRG
- SLC6A3
- SLC6A2
- FYN
- TACR2
- SLC6A4
- GALE
- HTR2A
- HTR2B
Mechanisms of action (all sources)
- ESR1 AGONIST
- ESR2 AGONIST
- ESR1 MODULATOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- TBXA2R
- AOX1
- CHRM2
- PTGS2
- ABCG2
- PDE5A
- NPY2R
- NR1H4
- NTSR1
- PDE3A
- PDE4A
- PDE4D
- KDM4A
- KDR
- PLK1
- PPARD
- PPARG
- PPP3CA
- PRKCA
- PTAFR
- NPY1R
- NPSR1
- NFE2L2
- PTPRC
- MMP9
- MMP1
- MC5R
- MC4R
- MC3R
- MAPT
- MAPK3
- MAPK1
- KCNH2
- MAOA
- LMNA
- LCK
- KMT2A
- ABCB1
- RORC
- RGS4
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- 5HT2A
- ACM1
- KSYK
- MDM2
- MDM4
- NF2L2
- NSD2
- NTM1A
- NTMT1
- PPM1D
- PRGR
- SC5A7
- SMAD2
- SYK
- TAAR1
- TNNC1
- TNNI3
- HSPB1
- GNA15
- GLI3
- CP19A
- ACM4
- ALR
- ANDR
- APAF
- BARD1
- BRCA1
- CP1A2
- GEMI
- CP2C9
- CP2D6
- CP3A4
- CP3A7
- ERR3
- GCR
- TNNT2
Drug classes
- Carcinogens
- Estrogens
- Estrogens, Non-Steroidal
- Hormones
- Noxae
- Antineoplastic Agents
- Antineoplastic Agents, Hormonal
- synthetic estrogen
ATC classes
- G03C · ESTROGENS
- L02A · HORMONES AND RELATED AGENTS
Cross-references
Synonyms
- STILBESTROL
- STILBETIN
- agostilben
- antigestil
- distilbene
- estrobene
- estromenin
- stilbestrol
- Dietilestilbestrol
- Stilbestro
- NSC-3070
- Apstil
- Distilbene
- Stilbestrol
- Stilbetin
- Stilboesterol
- Tampovagan
- Acnestrol
- Agostilben
- Antigestil
- Bufon
- Climaterine
- Comestrol
- Cyren
- DES
- Desma
- Destrol
- Diaethylstilboestrolum
- Diastyl
- Dibestrol
- Dicorvin
- Diethylstilbesterol
- Diethylstilbestrolum
- Diethylstilboesterol
- Dietilstilbestrolo
- Domestrol
- Dyestrol
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