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BMS-182874
SynDRA canonical compound SYN0000034 — structure-anchored drug synonym record
| Clinical phase | Phase 2 |
|---|
| Primary target(s) | EDNRA |
|---|
| Mechanism of action | Endothelin receptor antagonist |
|---|
All known targets
Mechanisms of action (all sources)
- Endothelin receptor antagonist
- EDNRA INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- CYP1A2
- CYP2C19
- CYP2C9
- CYP2D6
- CYP3A4
- EDNRB
- HDAC6
- HPGD
- HSD17B10
- KAT2A
- KDM4E
- TSHR
- USP1
- VDR
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Cross-references
Synonyms
- Bms 182874
- 5-Ddins
- CHEMBL267458
- 5-(dimethylamino)-N-(3,4-dimethyl-5-isoxazolyl)-1-naphthalenesulfonamide
- 1-Naphthalenesulfonamide, 5-(dimethylamino)-N-(3,4-dimethyl-5-isoxazolyl)-
- Tocris-1441
- AC1L3UAG
- SCHEMBL802730
- ZINC5803
- CHEBI:92993
- DTXSID60165205
- BDBM50034435
- NCGC00025164-01
- LS-173440
- L009159
- BRD-K56509348-003-01-3
- 5-Dimethylamino-naphthalene-1-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide
- 5-Dimethylamino-naphthalene-1-sulfonic acid (3,4-dimethyl-2,3-dihydro-oxazol-5-yl)-amide
- RefChem:917404
- DTXCID6087696
- MFCD00871737
- orb1701016
- AKOS040748001
- SY333712
- TS-08486
- HY-118497
- CS-0066140
- E87723
- T26841
- BRD-K56509348-003-02-1
- Bms 182874 hydrochloride
- SR-01000597801-1
- QYB70304
- T21790
- G78756
- TS-08204
- SR-01000597801
- DA-49772
- GLXC-02829
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