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CIPROFLOXACIN
SynDRA canonical compound SYN0000023 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | TOP2A |
|---|
| Mechanism of action | bacterial DNA gyrase inhibitor |
|---|
| Indication | otitis |
|---|
| Disease area | otolaryngology |
|---|
All known targets
- TOP2A
- Bact gyrA
- Bact gyrB
- mdtK
- gyrA
- TOP2B
- Stap-coc parC
- Hrh3
- Gabrq
- Gabrp
- Gabrg3
- Gabrg2
Mechanisms of action (all sources)
- DNA gyrase inhibitor
- Candi TMP1 INHIBITOR
- Bact gyrA; Bact gyrB MODULATOR
- Stap-coc parC MODULATOR
- gyrA INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- SLC47A2
- ABCB1
- MAPK3
- LCK
- LMNA
- MAOA
- MAPK1
- MAPK14
- MC3R
- KCNH2
- MC4R
- MC5R
- MLNR
- MMP1
- MMP9
- MRGPRX2
- KDM4E
- HTR7
- NPY2R
- HTR6
- HTR3A
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- HSD17B10
- HRH2
- HRH1
- HPGD
- HMGCR
- HDAC6
- GIPR
- GHSR
- NPY1R
- NR3C1
- GALC
- NTSR1
- TDP1
- TBXAS1
- TBXA2R
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
- Anti-Bacterial Agents
- Anti-Infective Agents
- Antineoplastic Agents
- Cytochrome P-450 CYP1A2 Inhibitors
- Cytochrome P-450 Enzyme Inhibitors
- Enzyme Inhibitors
- Metabolic Side Effects of Drugs and Substances
- Topoisomerase II Inhibitors
- Topoisomerase Inhibitors
- Quinolone Antimicrobial
- Cytochrome P450 1A2 Inhibitors
- Fluoroquinolone Antibacterial
ATC classes
- J01M · QUINOLONE ANTIBACTERIALS
- S03A · ANTIINFECTIVES
- COMBINATIONS OF ANTIBACTERIALS
Cross-references
Synonyms
- CETRAXAL
- CILOXAN
- CIPRO
- CIPRO HC
- CIPRO IN DEXTROSE 5% IN PLASTIC CONTAINER
- CIPRO IN SODIUM CHLORIDE 0.9% IN PLASTIC CONTAINER
- CIPRO XR
- CIPRODEX
- CIPROFLOXACIN AND DEXAMETHASONE
- CIPROFLOXACIN EXTENDED RELEASE
- CIPROFLOXACIN HYDROCHLORIDE
- ciprofloxacin hydrochloride
- ciprofloxacillin
- ciprofloxacine
- ciprofloxacin hydrochloride monohydrate
- ciprofloxacin HCl
- ciprofloxacin lactate
- Ciprofloxacine
- Ciprofloxacino
- Ciprofloxacinum
- BAY-O-9867 FREE BASE
- BAY-Q-3939
- BAYQ3939
- NSC-758467
- Ciprofloxacin component of ciprodex
- Otiprio
- Velmonit
- Ciprofloxacin XR
- Ciprobay
- Ciproxan
- Ciprofloxacina
- Cipro IV
- Ciproxina
- Ciprinol
- Bernoflox
- Ciprodar
- Cifloxin
Reported adverse events
- Tendinitis
- Peripheral neuropathy
- Acute exacerbation of chronic bronchitis
- Acute sinusitis
- Flu
- Eosinophilia
- Agitation
- Hypersensitivity
- Stevens-Johnson syndrome
- Erythema
- Irritability
- Tinnitus
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