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FLEROXACIN
SynDRA canonical compound SYN0000018 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Primary target(s) | TOP2A |
|---|
| Mechanism of action | topoisomerase inhibitor |
|---|
| Indication | diarrhea | enteritis | gonorrhea | respiratory tract infections |
|---|
| Disease area | gastroenterology | infectious disease |
|---|
All known targets
Mechanisms of action (all sources)
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ACHE
- KDM4E
- MMP9
- MMP1
- MLNR
- MC5R
- MC4R
- MC3R
- MAPK3
- MAPK14
- MAPK1
- MAOA
- LCK
- KCNH2
- ADORA1
- HTR6
- HTR3A
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- HRH3
- HRH2
- HRH1
- HMGCR
- HDAC6
- NPY1R
- NPY2R
- NR1I2
- NR3C1
- TBXAS1
- TBXA2R
- TACR2
- TACR1
- SLC6A4
- SLC6A3
- SLC6A2
- SLC29A1
- SIGMAR1
- SAMHD1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
- Anti-Infective Agents
- Antineoplastic Agents
- Enzyme Inhibitors
- Topoisomerase II Inhibitors
- Topoisomerase Inhibitors
ATC classes
- J01M · QUINOLONE ANTIBACTERIALS
Cross-references
Synonyms
- flerofloxacin
- megalocin
- megalone
- quinodis
- Fleroxacine
- Fleroxacino
- Megalocin
- AM-833
- RO-23-6240/000
- RO-236240
- RO-236240000
- Megalone
- FLRX
- Fleroxacinum
- Fleroxicin
- Megalosin
- Quinodis
- Fleroxacine [French]
- Fleroxacino [Spanish]
- Fleroxacinum [Latin]
- F0646
- Megalocin (TN)
- Megalone (TN)
- Quinodis (TN)
- Ro 23-6240
- Ro-236240
- Ro-23-6240/000
- Fleroxacin (JAN/USAN/INN)
- Fleroxacin [USAN:BAN:INN:JAN]
- 6,8-Difluoro-1-(2-fluoroethyl)-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid
- 6,8-Difluoro-1-(2-fluoroethyl)-1,4-dihydro-7-(4-methylpiperazino)-4-oxo-3-quinolinecarboxylic acid
- 6,8-Difluoro-1-(2-fluoroethyl)1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid
- 6,8-difluoro-1-(2-fluoroethyl)-7-(4-methyl-1-piperazinyl)-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid
- 6,8-difluoro-1-(2-fluoroethyl)-7-(4-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid
- 6,8-difluoro-1-(2-fluoroethyl)-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid-
- AM 833
- Fleroxacin (Quinodis)
- CHEBI:31810
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