← SynDRA
TAZOBACTAM
SynDRA canonical compound SYN0000017 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Mechanism of action | beta lactamase inhibitor |
|---|
| Indication | pneumonia |
|---|
| Disease area | infectious disease |
|---|
All known targets
- BlaGIL-1
- Stap-coc blaZ
- penP
- penB1
- oxa-63
- imiA
- blaZ
- blaUOE-1
- blaTEM-125
- blaTEM-1
- blaT-4
- blaT-3
Mechanisms of action (all sources)
- beta lactamase inhibitor
- Stap-coc blaZ INHIBITOR
- bla INHIBITOR
- blaT-3 INHIBITOR
- blaT-4 INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ESR2
- ESR1
- ACHE
- KCNH2
- MMP1
- MC5R
- MC4R
- MC3R
- MAPK3
- MAPK14
- MAPK1
- MAOA
- LCK
- KDR
- HTR6
- FLT1
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- HRH3
- HRH2
- HRH1
- HMGCR
- HDAC6
- MMP9
- NPY1R
- NPY2R
- PTGS2
- TBXAS1
- TBXA2R
- TACR2
- TACR1
- SLC6A4
- SLC6A3
- SLC6A2
- SIGMAR1
- SAMHD1
- PTPRC
- PTGS1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ANDR
- CREB1
- GCR
- GPR151
- NR1H4
- PPARD
- PPARG
- PRGR
- SMAD2
- SMAD3
- VDR
Drug classes
- beta Lactamase Inhibitors
- Anti-Bacterial Agents
- Anti-Infective Agents
- beta-Lactamase Inhibitors
- Enzyme Inhibitors
- beta Lactamase Inhibitor
ATC classes
- J01C · BETA-LACTAM ANTIBACTERIALS, PENICILLINS
Cross-references
Synonyms
- PIPERACILLIN AND TAZOBACTAM
- PIPERACILLIN AND TAZOBACTAM AND SODIUM CHLORIDE IN DUPLEX CONTAINER
- ZERBAXA
- ZOSYN
- ZOSYN IN PLASTIC CONTAINER
- Zerbaxa
- Zosyn
- tazobactam sodium
- YTR 830
- CL 298,741
- CL-298741
- NSC-759887
- YTR-830H
- TAZ
- CL298741
- YTR830H
- Piprataz (TN)
- Tazobactam (JAN/USAN/INN)
- Tazobactamum
- YTR 830H
- CHEBI:9421
- SE10G96M8W
- NSC 759887
- CXA201
- YTR830
- RefChem:891206
- DTXCID003634
- J01CG02
- Tazobactam acid
- MFCD00867002
- Tazobactam;Tazobactan acid
- YTR 830 H
- CL-298741;YTR-830H
- SR-01000872598
- Tazobactamum [INN-Latin]
- C10H12N4O5S
- UNII-SE10G96M8W
- CCRIS 2203
Reported adverse events
- Alanine aminotransferase increased
- Headache
- Hypotension
- Insomnia
- Nausea
- Phlebitis
- Rash
- Abdominal pain
- Alanine aminotransferase
- Arthralgia
- Aspartate aminotransferase
- Aspartate aminotransferase increased
Look up TAZOBACTAM in the interactive SynDRA portal →