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NALIDIXIC ACID
SynDRA canonical compound SYN0000009 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · OTC |
|---|
| Mechanism of action | bacterial DNA gyrase inhibitor |
|---|
| Indication | urinary tract infections |
|---|
| Disease area | infectious disease |
|---|
All known targets
- HTR2B
- PKM
- TOP2A
- TOP2B
- gyrA
- gyrB
Mechanisms of action (all sources)
- DNA gyrase inhibitor
- gyrA INHIBITOR
- gyrB INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- PTGS1
- PPARD
- KDR
- LMNA
- MAOA
- MBNL1
- NFE2L2
- NFKB1
- OPRM1
- PDE3A
- PDE4A
- PGR
- ABCC4
- KCNH2
- PTGS2
- RXRA
- SAMHD1
- SLC6A2
- SLC6A3
- SLC6A4
- SLCO1B1
- SLCO1B3
- TBXA2R
- TDP1
- KDM4E
- HTR1A
- ACHE
- CYP1A2
- ADORA3
- ADRA1A
- ADRA2A
- APEX1
- AR
- BAZ2B
- BLM
- CHRM1
- CHRM2
- CXCL8
- CYP2C19
- HSD17B10
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- 5HT2A
- CP1A2
- DRD2
- MDR1
- PLCG1
Drug classes
- Anti-Bacterial Agents
- Anti-Infective Agents
- Antineoplastic Agents
- Enzyme Inhibitors
- Topoisomerase II Inhibitors
- Topoisomerase Inhibitors
ATC classes
- J01M · QUINOLONE ANTIBACTERIALS
Cross-references
Synonyms
- NEGGRAM
- nalidic acid
- nalidixinic acid
- nalidixate
- nalidixic acid sodium
- nalidixic acid sodium salt
- Acide nalidixique
- Acido nalidixico
- Nalidixane
- Nalidixate
- NSC-82174
- WIN 18,320
- WIN-18320
- Mictral
- Nalix
- Neg gram
- Neggram
- Negram
- Uriben
- Uroneg
- Betaxina
- Cybis
- Dixiben
- Dixinal
- Eucistin
- Innoxalon
- Jicsron
- Kusnarin
- Nalidicron
- Nalidixan
- Nalidixic
- Nalidixin
- Nalitucsan
- Nalurin
- Narigix
- Naxuril
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