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PRAZOSIN
SynDRA canonical compound SYN0000003 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | ADRA2C |
|---|
| Mechanism of action | Adrenergic receptor antagonist |
|---|
| Indication | hypertension |
|---|
| Disease area | cardiology |
|---|
All known targets
- ADRA1B
- ADRA1D
- ADRA1A
- ADRA2A
- ADRA2B
- ADRA2C
- KCNH2
- ADORA3
- NQO2
- KCNH6
- KCNH7
- MMP1
Mechanisms of action (all sources)
- Adrenergic receptor antagonist
- ADRA1A ANTAGONIST
- Adrenergic receptor alpha-1 antagonist
- ADRA1D ANTAGONIST
- ADRA1B ANTAGONIST
- ADRA1A INVERSE AGONIST
- ADRA1B INVERSE AGONIST
- ADRA1D INVERSE AGONIST
- ADRA2A ANTAGONIST
- ADRA2B ANTAGONIST
- ADRA2C ANTAGONIST
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- DRD1
- OPRK1
- ABCG2
- TSPO
- SIGMAR1
- ADRB2
- AGTR1
- HTR5A
- ABCB1
- MLNR
- MPG
- MTOR
- MUTYH
- NEIL1
- NEIL2
- NFE2L2
- NPY1R
- NFKB1
- NPC1
- MC4R
- NPY2R
- NR3C1
- NTSR1
- OGG1
- OPRD1
- MC5R
- MAPT
- MC3R
- MBD4
- HRH3
- HRH4
- HSD17B10
- HTR1B
- HTR1E
- HTR3A
- HTR6
- HTR7
- IDH1
- KDM4E
- LCK
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ADA2B
- ADA2C
- SYK
- STK33
- SC5A7
- NTM1A
- NSD2
- NR1H4
- MDM4
- MDM2
- MCL1
- KSYK
- IL1B
- IFNG
- IFNB1
- HLAB
- HDAC9
- GEMI
- CP3A4
- BRCA1
- BARD1
- ATRX
- ANDR
- TADA2A
Drug classes
- Adrenergic alpha-Antagonists
- alpha-Adrenergic Blocker
- Adrenergic Agents
- Adrenergic alpha-1 Receptor Antagonists
- Adrenergic Antagonists
- Antihypertensive Agents
- Cardiovascular Agents
- Neurotransmitter Agents
ATC classes
- C02C · ANTIADRENERGIC AGENTS, PERIPHERALLY ACTING
- ANTIHYPERTENSIVES AND DIURETICS IN COMBINATION
Cross-references
Synonyms
- MINIPRESS
- MINIPRESS XL
- MINIZIDE
- Minipress
- PRAZOSIN HYDROCHLORIDE
- prazosin hydrochloride
- furazosin
- prazosin HCl
- Prazosine
- Prazosina
- CP-122991
- Furazosin
- Justac
- Lentopres
- Prazocin
- Prazosinum
- Prazosin HCl
- TNP00312
- CP-12299
- Hypovase (TN)
- Minipress (TN)
- Prazosin (INN)
- Prazosin [INN:BAN]
- Prazosina [INN-Spanish]
- Prazosine [INN-French]
- Prazosinum [INN-Latin]
- Vasoflex (TN)
- [3H]-Prazosin
- CHEMBL2
- HSDB 3298
- CHEBI:8364
- XM03YJ541D
- Hypovase
- NCGC00016740-13
- PRAZOSIN [INN]
- CAS-19216-56-9
- EINECS 242-885-8
- BRN 0768345
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